Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts-Reference-Cited by-同舟云学术

Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts

Published:2019-11 Issue:2 Volume:208 Page:182-190
ISSN:1047-8477
Container-title:Journal of Structural Biology
language:en
Short-container-title:Journal of Structural Biology

Author:

Wagner Tristan,Boyko Alexandra^ORCID,Alzari Pedro M.,Bunik Victoria I.,Bellinzoni Marco^ORCID

Funder

Centre National de la Recherche Scientifique

Russian Science Foundation

Institut Pasteur

Publisher

Elsevier BV

Subject

Structural Biology

Reference45 articles.

1. Differential aspartate usage identifies a subset of cancer cells particularly dependent on OGDH;Allen;Cell Reports,2016

2. A thiamin-bound, pre-decarboxylation reaction intermediate analogue in the pyruvate dehydrogenase E1 subunit induces large scale disorder-to-order transformations in the enzyme and reveals novel structural features in the covalently bound adduct;Arjunan;J. Biol. Chem.,2006

3. Directed regulation of multienzyme complexes of 2-oxo acid dehydrogenases using phosphonate and phosphinate analogs of 2-oxo acids;Artiukhov;Biochemistry Mosc.,2016

4. Influence of allosteric regulators on individual steps in the reaction catalyzed by Mycobacterium tuberculosis 2-hydroxy-3-oxoadipate synthase;Balakrishnan;J. Biol. Chem.,2013

5. α-Hydroxy-β-keto acid rearrangement-decarboxylation: impact on thiamine diphosphate-dependent enzymatic transformations;Beigi;Org. Biomol. Chem.,2013

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase;Nature Communications;2023-08-10

2. High resolution cryo-EM and crystallographic snapshots of the large actinobacterial 2-oxoglutarate dehydrogenase: an all-in-one fusion with unique properties;2023-02-23

3. Harnessing Rare Actinomycete Interactions and Intrinsic Antimicrobial Resistance Enables Discovery of an Unusual Metabolic Inhibitor;mBio;2022-06-28

4. Structural basis for the activity and regulation of human α-ketoglutarate dehydrogenase revealed by Cryo-EM;Biochemical and Biophysical Research Communications;2022-04

5. Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes;Life;2021-04-29