Structural basis for the activity and regulation of human α-ketoglutarate dehydrogenase revealed by Cryo-EM

Author:

Zhong Youhuan,Gao Yuanzhu,Zhou Dejian,Ma Xiaomin,Chen Huan,Xu Yingjie,Yang WenORCID,Yu XiangORCID

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference27 articles.

1. The alpha-ketoglutarate dehydrogenase complex in cancer metabolic plasticity;Vatrinet;Cancer Metabol.,2017

2. Reductions in the mitochondrial enzyme alpha-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?;Chen;J. Neurochem.,2016

3. Behavioral impact of the regulation of the brain 2-oxoglutarate dehydrogenase complex by synthetic phosphonate analog of 2-oxoglutarate: implications into the role of the complex in neurodegenerative diseases;Trofimova;Int. J. Alzheimer's Dis.,2010

4. An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease;Mizuno;Ann. Neurol.,1994

5. 2-Ketoglutarate dehydrogenase deficiency, a rare cause of primary hyperlactataemia: report of a new case;Guffon;J. Inherit. Metab. Dis.,1993

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