Biotransformation of 17β-hydroxy-11β-(4-dimethylaminophenyl)17α-1-propynyl-estra-4,9-dien-3-one (RU486) in rat hepatoma variants
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference24 articles.
1. RU486;Ulmann;Sci Am,1990
2. Pharmacokinetics of RU486;Deraedt,1985
3. The P450 superfamily: uptake on new sequences, gene mapping, accession numbers, early trivial names of enzymes and nomenclature;Nelson;DNA Cell Biol,1993
4. The steroid antagonist RU38486 is metabolized by the liver microsomal P450 monooxygenases;Chasserot-Golaz;Biochem Biophys Res Commun,1990
5. Metabolism of testosterone and dihydrotestosterone in cultured hepatoma cells;De Moor;J Steroid Biochem,1975
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