An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference38 articles.
1. Psychotomometics as anticholinergic agents. I. Cyclohexylpiperidene derivatives: anticholinesterase activity and antagonistic activity to acetylcholine;Maayani;Biochem Pharmacol,1974
2. Oral tetrahydroaminoacridine in long term treatment of senile dementia, Alzheimer type;Summers;N Engl J Med,1986
3. Tetrahydroaminoacridine and lecithin in Alzheimer's disease;Gauthier,1988
4. A controlled trial of tacrine in Alzheimer's patients;Farlow;JAMA,1992
5. Clinical experience with and side effects of tacrine hydrochloride in Alzheimer's disease: a pilot study;Forsyth;Age Ageing,1989
Cited by 102 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Chemical Structural Alert and Reactive Metabolite Concept as Applied in Medicinal Chemistry to Minimize the Toxicity of Drug Candidates;Drug Metabolism Handbook;2022-11-18
2. Drug‐Metabolism Enzymes and Transporter Activities as Risk Factors of Selected Marketed Drugs Associated with Drug‐Induced Fatalities;Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity;2021-07-02
3. An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes – application to establishing CYP2C8 inhibitor selectivity;European Journal of Pharmaceutical Sciences;2021-07
4. Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6;Journal of Medicinal Chemistry;2020-07-24
5. Chlorinated tacrine analogs: Design, synthesis and biological evaluation of their anti-cholinesterase activity as potential treatment for Alzheimer’s disease;Bioorganic Chemistry;2019-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3