Chlorinated tacrine analogs: Design, synthesis and biological evaluation of their anti-cholinesterase activity as potential treatment for Alzheimer’s disease
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry
Reference58 articles.
1. Synthesis and acetylcholinesterase inhibitory activity of novel tetrahydroquinoline and pyrazolo [3, 4-b]-tetrahydroquinoline derivatives As potential agents for treatment of Alzheimer's disease;El-Tombary;Alexandria J. Pharm. Sci.,2008
2. Synthesis and biological evaluation of new oxopyrrolidine derivatives as inhibitors of acetyl cholinesterase and β amyloid protein as anti–Alzheimer’s agents;Mohamed;Bioorg. Chem.,2018
3. Design, synthesis and evaluation of novel dual monoamine-cholinesterase inhibitors as potential treatment for Alzheimer’s disease;Liu;Neuropharmacology,2016
4. Ethyl nitrobenzoate: a novel scaffold for cholinesterase inhibition;Yeong;Bioorg. Chem.,2017
5. Synthesis and biological evaluation of some tacrine analogs: study of the effect of the chloro substituent on the acetylcholinesterase inhibitory activity;Ragab;Monatshefte für Chemie-Chemical Monthly,2016
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