The activity of verapamil as a resistance modifier in vitro in drug resistant human tumour cell lines is not stereospecific

Author:

Plumb Jane A.,Milroyf Robert,Kaye Stanley B.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference31 articles.

1. Internal duplication and homology to bacterial transport proteins in the mdrl (P-glycoprotein) gene for multidrug-resistant human cells;Chen;Cell,1986

2. Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia;Inaba;Cancer Res,1979

3. Expression of a multidrug resistance gene in human cancers;Goldstein;J Natl Cancer Inst,1989

4. Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumour cells following incubation with calcium antagonists and calmodulin inhibitors;Tsuruo;Cancer Res,1982

5. Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of l- andd-verapamil examined with a stable isotope technique;Vogelgesang;Br J Clin Pharmacol,1984

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