Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of L- and D-verapamil examined with a stable isotope technique.-Reference-Cited by-同舟云学术

Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of L- and D-verapamil examined with a stable isotope technique.

Published:1984-11 Issue:5 Volume:18 Page:733-740
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:British Journal of Clinical Pharmacology

Author:

Vogelgesang B,Echizen H,Schmidt E,Eichelbaum M

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.1984.tb02536.x/fullpdf

Reference22 articles.

1. Clinical pharmacokinetics of verapamil in patients with atrial fibrillation.;Anderson;Eur. J. clin. Pharmac.,1982

2. The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias.;Barrett;Br. J. Pharmac.,1968

3. Effects of verapamil on P-R intervals in relation to verapamil plasma levels following single i.v. and oral administration and during chronic treatment.;Eichelbaum;Klin. Wochenschr.,1980

4. Superiority of stable isotope techniques in the assessment of the bioavailability of drugs undergoing extensive first-pass elimination. Studies of the relative bioavailability of verapamil tablets.;Eichelbaum;Eur. J. clin. Pharmac.,1981b

5. The metabolism of (d,l- 14 C) verapamil in man.;Eichelbaum;Drug Metab. Dispos.,1979

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