Deoxyuridylate effects on thymidylate synthase-5-fluorodeoxyuridylate-folate ternary complex formation

Author:

Spears Colin Paul,Hayes Andrea A.,Shahinian Antranik H.,Danenberg Peter V.,Frösing Roland,Gustavsson Bengt G.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference44 articles.

1. Relationship of cellular folate cofactor pools to the activity of 5-fluorouracil;Yin;Mol Pharmacol,1982

2. Cytotoxicity of 5-fluoro-2'-deoxyuridine: requirement for reduced folate cofactors and antagonism by metho-trexate;Ullman,1978

3. Folinic acid augmentation of the effects of fluoropyrimidines in murine and human leukemic cells;Keyomarsi;Cancer Res,1986

4. Cytotoxicity of floxuridine and 5-fluorouracil in human T-lymphoblast leukemia cells: enhancement by leucovorin;Mini;Cancer Treat Rep,1987

5. Overview of current status and future direction of clinical trials with 5-fluorouracil in combination with folinic acid;Grem;Cancer Treat Rep,1987

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