Expression and Clinical Significance of Methylenetetrahydrofolate Reductase in Patients with Colorectal Cancer

Author:

Odin Elisabeth,Wettergren Yvonne,Carlsson Göran,Danenberg Peter V.,Termini Angelo,Willén Roger,Gustavsson Bengt

Publisher

Elsevier BV

Subject

Gastroenterology,Oncology

Reference44 articles.

1. Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase;Kang;Am J Hum Genet,1988

2. Plasma homocysteine levels related to interactions between folate status and methylenetetrahydrofolate reductase: a study in 52 healthy subjects;Zittoun;Metabolism,1998

3. Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene;Stern;Cancer Epidemiol Biomarkers Prev,2000

4. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase;Frosst;Nat Genet,1995

5. A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status;Friso;Proc Natl Acad Sci U S A,2002

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