Author:
Jackman Ann L.,Newell David R.,Gibson William,Jodrell Duncan I.,Taylor Gordon A.,Bishop Joel A.,Hughes Leslie R.,Hilary Calvert A.
Subject
Pharmacology,Biochemistry
Reference38 articles.
1. A potent antitumour quinazoline inhibitor of thymidylate synthetase: synthesis, biological properties and therapeutic results in mice;Jones;Eur J Cancer,1981
2. Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (Q1L2) system in vitro and in L1210 in vivo;Jackman;Cancer Res,1990
3. Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, CB3717, on human lymphoblastoid cells;Jackson;Biochem Pharmacol,1983
4. Kinetics and mechanism of interaction of 10-propargyl-5,8-dideazafolate with thymidylate synthase;Pogolotti;J Med Chem,1986
5. Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase and KB cells containing different levels of dihydrofolate reductase;Cheng;Cancer Res,1985
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