Stereoselective functionalization of pyrrolidinone moiety towards the synthesis of salinosporamide A-Reference-Cited by-同舟云学术

Stereoselective functionalization of pyrrolidinone moiety towards the synthesis of salinosporamide A

Published:2012-08 Issue:32 Volume:68 Page:6504-6512
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Barbion Julien,Sorin Geoffroy,Selkti Mohamed,Kellenberger Esther,Baati Rachid,Santoro Stefano,Himo Fahmi,Pancrazi Ange,Lannou Marie-Isabelle,Ardisson Janick

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference106 articles.

1. For the isolation and biology of salinosporamide A, see:

2. Salinosporamide A: A Highly Cytotoxic Proteasome Inhibitor from a Novel Microbial Source, a Marine Bacterium of the New Genus Salinospora

3. A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

4. Crystal Structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in Complex with the 20S Proteasome Reveal Important Consequences of β-Lactone Ring Opening and a Mechanism for Irreversible Binding

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