Heck reaction of ortho-substituted iodobenzenes with α,β-unsaturated nitriles as a key step in the synthesis of tetrahydro-2-benzazepines and hexahydro-3-benzazocines
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference43 articles.
1. Synthesis and dopaminergic binding of 2-aryldopamine analogs: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes
2. Fenoldopam: A New Dopamine Agonist for the Treatment of Hypertensive Urgencies and Emergencies
3. Synthesis and structure/NMDA receptor affinity relationships of 1-substituted tetrahydro-3-benzazepines
4. Asymmetric Synthesis of 1-Substituted Tetrahydro-3-benzazepines as NMDA Receptor Antagonists
5. Discovery and Structure−Activity Relationship of (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT2C Receptor Agonist for the Treatment of Obesity
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