An unexpected aziridination/rearrangement/oxidation tandem reaction leading to the total synthesis of (−)-mersicarpine-Reference-Cited by-同舟云学术

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An unexpected aziridination/rearrangement/oxidation tandem reaction leading to the total synthesis of (−)-mersicarpine

Published:2017-07 Issue:29 Volume:73 Page:4201-4205
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Zhang Yun,Xue Yibin,Luo Tuoping

Funder

National “Young 1000 Talent Plan” Program

College of Chemistry and Molecular Engineering, Peking University

Peking-Tsinghua Center for Life Sciences

National Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference86 articles.

1. Chemistry and biology of monoterpene indole alkaloid biosynthesis

2. Medicinal Natural Products;Dewick,2001

3. Enantioselective synthesis of Iboga alkaloids and vinblastine via rearrangements of quaternary ammoniums

4. In vitro oxidative metabolism study of (−)-rhazinilam

5. Hemisynthesis of rhazinilam analogues: structure - activity relationships on tubulin-microtubule system

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1. Syntheses of Mersicarpine, a Monoterpenoid Indole Alkaloid with an Atypical Tetracyclic Structure;ChemistrySelect;2022-07-08

2. Total synthesis of (±)-mersicarpine following a 6-exo-trig radical cyclization;Organic & Biomolecular Chemistry;2022

3. A short total synthesis of (±)-mersicarpine via visible light-induced cascade photooxygenation;Chemical Communications;2022

4. Total synthesis of the pseudoindoxyl class of natural products;Organic & Biomolecular Chemistry;2021

5. A novel translation inhibitor, mersicarpine, inhibits S-phase progression and induces apoptosis in HL60 cells;Bioscience, Biotechnology, and Biochemistry;2021-01

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