An improved and practical synthesis of 5,5-dimethyl-3-(2-propoxy)-4-(4-methanesulfonylphenyl)-2-(5H)-furanone (DFP—a selective inhibitor of cyclooxygenase-2)-Reference-Cited by-同舟云学术

An improved and practical synthesis of 5,5-dimethyl-3-(2-propoxy)-4-(4-methanesulfonylphenyl)-2-(5H)-furanone (DFP—a selective inhibitor of cyclooxygenase-2)

Published:2003-09 Issue:40 Volume:59 Page:7915-7920
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Padakanti Srinivas,Pal Manojit,Yeleswarapu Koteswar Rao

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference38 articles.

1. SAR in the alkoxy lactone series: the discovery of DFP, a potent and orally active COX-2 inhibitor

2. The discovery of rofecoxib, [MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor

3. Human cyclooxygenase-2 cDNA.

4. Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells.

Cited by 42 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. One pot multi-component synthesis of novel functionalized pyrazolo furan-2(5H)-one derivatives: in vitro, DFT, molecular docking, and pharmacophore studies, as coronavirus inhibitors;Molecular Diversity;2024-08-22

2. GO@dopamine-Cu as a Green Nanocatalyst for the Efficient Synthesis of Fully Substituted Dihydrofuran-2(5H)-ones;Journal of the Turkish Chemical Society Section A: Chemistry;2023-11-24

3. Trans‐metallated chlorophyllin by copper supported on silica‐coated magnetic nanoparticles as an efficient and green catalyst for the synthesis of furan‐2(5H)‐ones;Applied Organometallic Chemistry;2023-02-24

4. Glycerol Derived carbon-SO₃H: A Green Recyclable Catalyst toward the Access of Functionalised 2,5-Dihydrofuran-3-Carboxylates;Polycyclic Aromatic Compounds;2022-02-04

5. Synthesis of Heterocycles Over Nanoporous Zeolites;Handbook of Nanomaterials and Nanocomposites for Energy and Environmental Applications;2020-12-08