Clinical and preclinical activity of 2′,2′- difluorodeoxycytidine (gemcitabine)

Author:

Lund Birthe,Kristjansen Paul E.G.,Hansen Heine H.

Publisher

Elsevier BV

Subject

Radiology Nuclear Medicine and imaging,Oncology,General Medicine

Reference35 articles.

1. Antiviral activity of 2′,2′-difluorodeoxycytidine;Delong;Am. Soc. Microbiol. Abstracts,1986

2. Evaluation of the antitumor activity of gemcitabine (2′,2′-difluoro-2′-deoxycytidine);Hertel;Cancer Res.,1990

3. Synthesis of 2-deoxy-2′,2′-difluoro- D-ribose and 2-deoxy-2′,2′-difluoro-D-ribofuranosyl nucleosides;Hertel;J. Org. Chem.,1988

4. 19-F-NMR- spectroscopic analysis and in vivo activity of difluorodeoxycytidine (dFdC) in two small cell lung cancer xenografts. Preliminary results;Kristjansen,1990

5. Action of 2′,2′- difluorodeoxycytidine on DNA synthesis;Huang;Cancer Res.,1991

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