8-Methoxypsoralen Induces Apoptosis by Upregulating p53 and Inhibits Metastasis by Downregulating MMP-2 and MMP-9 in Human Gastric Cancer Cells
Author:
Affiliation:
1. Rare Disease Research Center, Korea Research Institute of Bioscience & Biotechnology (KRIBB), Daejeon 34141, Republic of Korea
2. Department of New Drug Development, Chungnam National University, Daejeon 34134, Republic of Korea
Funder
National Research Foundation of Korea
Ministry of Science and ICT of Korea
Publisher
The Korean Society of Applied Pharmacology
Subject
Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry
Link
http://pdf.medrang.co.kr/BT2/2023/031/BT031-02-219.pdf
Reference29 articles.
1. Studies on mechanism of 8-methoxypsoralen–DNA interaction in the dark
2. UVA-activated 8-methoxypsoralen (PUVA) causes G2/M cell cycle arrest in Karpas 299 T-lymphoma cells
3. Role of p53 in the progression of gastric cancer
4. PUVA-induced apoptosis involves mitochondrial dysfunction caused by the opening of the permeability transition pore
5. TP53 and gastric carcinoma: A review
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