Adenoviral-mediated transfer of Escherichia coli uracil phosphoribosyltransferase (UPRT) gene to modulate the sensitivity of the human colon cancer cells to 5-fluorouracil

Author:

Koyama F,Sawada H,Fujii H,Hamada H,Hirao T,Ueno M,Nakano H

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference31 articles.

1. Fluorouracil;Pinedo;J. Clin. Oncol.,1988

2. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines;Van Triest;Clin. Cancer Res.,1999

3. Disruption of p53 in human cancer cells alters the responses to therapeutic agents;Bunz;J. Clin. Invest.,1999

4. Response to fluorouracil therapy in cancer patients;Eienne;J. Clin. Oncol.,1995

5. A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil;Beck;Eur. J. Cancer,1994

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