Frequency of Uridine Monophosphate Synthase Gly213Ala Polymorphism in Caucasian Gastrointestinal Cancer Patients and Healthy Subjects, Investigated by Means of New, Rapid Genotyping Assays-Reference-Cited by-同舟云学术

Frequency of Uridine Monophosphate Synthase Gly213Ala Polymorphism in Caucasian Gastrointestinal Cancer Patients and Healthy Subjects, Investigated by Means of New, Rapid Genotyping Assays

Published:2011-10 Issue:10 Volume:15 Page:691-695
ISSN:1945-0265
Container-title:Genetic Testing and Molecular Biomarkers
language:en
Short-container-title:Genetic Testing and Molecular Biomarkers

Author:

Gusella Milena¹²,Bertolaso Laura²,Bolzonella Caterina²,Pasini Felice¹,Padrini Roberto³

Affiliation:

1. Department of Oncology, Rovigo General Hospital, Rovigo, Italy.

2. Laboratory of Pharmacology and Molecular Biology, Trecenta General Hospital, Rovigo, Italy.

3. Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy.

Publisher

Mary Ann Liebert Inc

Subject

Genetics (clinical),General Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/gtmb.2011.0021

Reference17 articles.

1. MTHFR C677T and A1298C Polymorphisms

2. Relationships between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyltransferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma

3. Pharmacogenetic Analyses of a Phase III Trial in Metastatic Gastroesophageal Adenocarcinoma With Fluorouracil and Leucovorin Plus Either Oxaliplatin or Cisplatin: A Study of the Arbeitsgemeinschaft Internistische Onkologie

4. Orotate Phosphoribosyltransferase Gene Polymorphism Predicts Toxicity in Patients Treated with Bolus 5-Fluorouracil Regimen

5. Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer

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