GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-β1/SMAD3 pathway-Reference-Cited by-同舟云学术

GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-β1/SMAD3 pathway

Published:2024-03 Issue: Volume:152 Page:155772
ISSN:0026-0495
Container-title:Metabolism
language:en
Short-container-title:Metabolism

Author:

Jurado-Aguilar Javier,Barroso Emma,Bernard Maribel,Zhang Meijian,Peyman Mona,Rada Patricia,Valverde Ángela M.,Wahli Walter,Palomer Xavier,Vázquez-Carrera Manuel

Funder

Espana Ministerio de Ciencia e Innovacion

China Scholarship Council

Publisher

Elsevier BV

Reference43 articles.

1. Knocking on GDF15’s door for the treatment of type 2 diabetes mellitus;Aguilar-Recarte;Trends Endocrinol Metab,2022

2. The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL;Emmerson;Nat Med,2017

3. GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates;Mullican;Nat Med,2017

4. Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15;Hsu;Nature,2017

5. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand;Yang;Nat Med,2017

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Association of biomarkers and Barthel Index with occurrence of age‐related adverse health outcomes in individuals with diabetes;Journal of Diabetes Investigation;2024-08-14

2. Emerging mechanisms of non-alcoholic steatohepatitis and novel drug therapies;Chinese Journal of Natural Medicines;2024-08

3. Hepatic noradrenergic innervation acts via CREB/CRTC2 to activate gluconeogenesis during cold;Metabolism;2024-08

4. Roles of transforming growth factor-β signaling in liver disease;World Journal of Hepatology;2024-07-27

5. Circulating total and H-specific GDF15 levels are elevated in subjects with MASLD but not in hyperlipidemic but otherwise metabolically healthy subjects with obesity;Cardiovascular Diabetology;2024-05-18