Chlorambucil-conjugated PI-polyamides (Chb-M’), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutation
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference18 articles.
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2. Tailoring medulloblastoma treatment through genomics: making a change, one subgroup at a time;Holgado;Annu. Rev. Genom. Hum. Genet,2017
3. Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial;Goschzik;Lancet Oncol.,2018
4. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition;Kool;Canc. Cell,2014
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Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Intragland Expression of the Shh Gene Alleviates Irradiation-Induced Salivary Gland Injury through Microvessel Protection and the Regulation of Oxidative Stress;Antioxidants;2024-07-26
2. Chb-M′, an Inhibitor of the RUNX Family Binding to DNA, Induces Apoptosis in p53-Mutated Non-Small Cell Lung Cancer and Inhibits Tumor Growth and Repopulation In Vivo;Journal of Medicinal Chemistry;2024-05-28
3. Anticancer Activities of DNA-Alkylating Pyrrole–Imidazole Polyamide Analogs Targeting RUNX Transcription Factors against p53-Mutated Pancreatic Cancer PANC-1 Cells;Journal of Medicinal Chemistry;2023-08-22
4. Corrigendum to “Chlorambucil-conjugated PI-polyamide (Chb-M’), a transcription inhibitor of the RUNX family, has anti-tumor activity against SHH-type medulloblastoma with p53 mutation” [Biochem. Biophys. Res. Commun. 620 (10 September 2022) 150–157];Biochemical and Biophysical Research Communications;2023-05
5. Sex differences in methylation profiles are apparent in medulloblastoma, particularly among SHH tumors;Frontiers in Oncology;2023-03-24
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