Hepatic NPC1L1 promotes hyperlipidemia in LDL receptor deficient mice
Author:
Funder
China Scholarship Council
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference39 articles.
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2. Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption;Altmann;Science,2004
3. Niemann-Pick C1 like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis;Davis;J. Biol. Chem.,2004
4. Niemann-Pick C1 like 1 (NPC1L1) an intestinal sterol transporter;Davis;Biochim. Biophys. Acta,2009
5. Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe;Temel;JCI (J. Clin. Investig.),2007
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1. Curcumin protects against high-fat diet-induced nonalcoholic simple fatty liver by inhibiting intestinal and hepatic NPC1L1 expression via down-regulation of SREBP-2/HNF1α pathway in hamsters;The Journal of Nutritional Biochemistry;2023-09
2. m6A-related bioinformatics analysis and functional characterization reveals that METTL3-mediated NPC1L1 mRNA hypermethylation facilitates progression of atherosclerosis via inactivation of the MAPK pathway;Inflammation Research;2022-12-30
3. Molecular cloning and characterization of NPC1L1 in the Chinese tree shrew (Tupaia belangeri chinensis);Molecular Biology Reports;2021-10-30
4. Differences between phytosterols with different structures in regulating cholesterol synthesis, transport and metabolism in Caco-2 cells;Journal of Functional Foods;2020-02
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