Molecular cloning and characterization of NPC1L1 in the Chinese tree shrew (Tupaia belangeri chinensis)-Reference-Cited by-同舟云学术

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Molecular cloning and characterization of NPC1L1 in the Chinese tree shrew (Tupaia belangeri chinensis)

Published:2021-10-30 Issue:12 Volume:48 Page:7975-7984
ISSN:0301-4851
Container-title:Molecular Biology Reports
language:en
Short-container-title:Mol Biol Rep

Author:

Kui Xiuying,Qiu Dandan,Wang Wenguang,Li Na,Tong Pinfen,Sun Xiaomei,Jin Liangzi,Deng Wei,Dai Jiejie,Lu Caixia^ORCID

Funder

Yunnan health training project of high-level talents

Yunnan science and technology talent and platform program

Kunming Science and technology innovation team

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s11033-021-06829-5.pdf

Reference49 articles.

1. Davies JP, Levy B, Ioannou YA (2000) Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1. Genomics 65:137–145. https://doi.org/10.1006/geno.2000.6151

2. Wang LJ, Wang J, Li N, Ge L, Li BL, Song BL (2011) Molecular characterization of the NPC1L1 variants identified from cholesterol low absorbers. J Biol Chem 286:7397–7408. https://doi.org/10.1074/jbc.M110.178368

3. Temel RE, Tang W, Ma Y, Rudel LL, Willingham MC, Ioannou YA, Davies JP, Nilsson LM, Yu L (2007) Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe. J Clin Invest 117:1968–1978. https://doi.org/10.1172/JCI30060

4. Toyoda Y, Takada T, Umezawa M, Tomura F, Yamanashi Y, Takeda K, Suzuki H (2019) Identification of hepatic NPC1L1 as an NAFLD risk factor evidenced by ezetimibe-mediated steatosis prevention and recovery. FASEB Bioadv 1:283–295. https://doi.org/10.1096/fba.2018-00044

5. Yu J, Li X, Matei N, McBride D, Tang J, Yan M, Zhang JH (2018) Ezetimibe, a NPC1L1 inhibitor, attenuates neuronal apoptosis through AMPK dependent autophagy activation after MCAO in rats. Exp Neurol 307:12–23. https://doi.org/10.1016/j.expneurol.2018.05.022

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