Screening of a novel free fatty acid receptor 1 (FFAR1) agonist peptide by phage display and machine learning based-amino acid substitution
Author:
Funder
Japan Society for the Promotion of Science
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference21 articles.
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2. Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40;Itoh;Nature,2003
3. Free fatty acid receptor 1 as a novel therapeutic target for type 2 diabetes mellitus-current status;Eleazu;Chem. Biol. Interact.,2018
4. Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules;Briscoe;Br. J. Pharmacol.,2006
5. A selective GPR40 (FFAR1) agonist LY2881835 provides immediate and durable glucose control in rodent models of type 2 diabetes;Chen;Pharmacol. Res. Perspect.,2016
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