Restoring wild-type conformation and DNA-binding activity of mutant p53 is insufficient for restoration of transcriptional activity

Author:

Brazda Vaclav,Muller Petr,Brozkova Kristyna,Vojtesek Borivoj

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference36 articles.

1. Rescuing the function of mutant p53;Bullock;Nat. Rev. Cancer,2001

2. Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome;Sigal;Cancer Res.,2000

3. Strategies for manipulating the p53 pathway in the treatment of human cancer;Hupp;Biochem. J.,2000

4. Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations;Soussi;Hum. Mutat.,2005

5. p53 gene mutation: software and database;Beroud;Nucleic Acids Res.,1998

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