Rescuing the function of mutant p53
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
Link
http://www.nature.com/articles/35094077.pdf
Reference70 articles.
1. Hanahan, D. & Weinberg, R. A. The hallmarks of cancer. Cell 100, 57–70 (2000).
2. Finette, B. A., Homans, A. C. & Albertini, R. J. Emergence of genetic instability in children treated for leukemia. Science 288, 514–517 (2000).
3. Komarov, P. G. et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285, 1733–1737 (1999).Traditional cancer therapies are invasive. DNA damage can occur in healthy cells and induce p53-dependent apoptosis. This paper describes an inhibitor of p53 that protects against these effects.
4. Sherr, C. J. The Pezcoller lecture: cancer cell cycles revisited. Cancer Res. 60, 3689–3695 (2000).
5. Hupp, T. R., Lane, D. P. & Ball, K. L. Strategies for manipulating the p53 pathway in the treatment of human cancer. Biochem. J. 352, 1–17 (2000). A recent review highlighting the progress of new approaches to cancer therapy based on restoring the p53 tumour-suppressor pathway.
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