Aβ40(L17A/F19A) mutant diminishes the aggregation and neurotoxicity of Aβ40-Reference-Cited by-同舟云学术

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Aβ40(L17A/F19A) mutant diminishes the aggregation and neurotoxicity of Aβ40

Published:2011-02 Issue:1 Volume:405 Page:91-95
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Chen Yi-Ru,Huang Hsien-bin,Lo Chi-Jen,Wang Chih-Ching,Su Chia-Li,Liu Hsin-Tzu,Shiao Ming-Shi,Lin Ta-Hsien,Chen Yi-Chen

Funder

National Science Council of Taiwan, ROC

Taipei Veterans General Hospital, Taiwan, Republic of China

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference21 articles.

1. The molecular pathology of Alzheimer’s disease;Selkoe;Neuron,1991

2. The amyloid beta protein gene is not duplicated in brains from patients with Alzheimer’s disease;Tanzi;Science,1987

3. Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1;Li;Nature,2000

4. Beta-secretase cleavage of Alzheimer’s amyloid precursor protein by the transmembrane aspartic protease BACE;Vassar;Science,1999

5. Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability;Dahlgren;J. Biol. Chem.,2002

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1. How Single Site Mutations Can Help Understanding Structure Formation of Amyloid β₁₋₄₀;Macromolecular Bioscience;2023-03-10

2. Humanin Blocks the Aggregation of Amyloid-β Induced by Acetylcholinesterase, an Effect Abolished in the Presence of IGFBP-3;Biochemistry;2020-05-08

3. Conformational Characterization of Native and L17A/F19A-Substituted Dutch-Type β-Amyloid Peptides;International Journal of Molecular Sciences;2020-04-07

4. A-type EGCG dimer, a new proanthocyanidins dimer from persimmon fruits, interacts with the amino acid residues of Aβ40 which possessed high aggregation-propensity and strongly inhibits its amyloid fibrils formation;Journal of Functional Foods;2019-01

5. Molecular insights into the effect L17A/F19A double mutation on the structure and dynamics of Aβ 40 : A molecular dynamics simulation study;Journal of Cellular Biochemistry;2018-08-04

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