In vitro Blood–Brain barrier model based on recombinant spider silk protein nanomembranes for evaluation of transcytosis capability of biomolecules

Author:

Hjelm Linnea CharlottaORCID,Hedhammar MyORCID,Löfblom JohnORCID

Funder

Brain Foundation

Knut and Alice Wallenberg Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference31 articles.

1. The blood-brain barrier: an engineering perspective;Wong;Front. Neuroeng.,2013

2. Bivalent brain shuttle increases antibody uptake by monovalent binding to the transferrin receptor;Hultqvist;Theranostics,2017

3. Blood-brain barrier and delivery of protein and gene therapeutics to brain;Pardridge;Front. Aging Neurosci.,2020

4. Transcytosis to cross the blood brain barrier, new advancements and challenges;Pulgar;Front. Neurosci.,2019

5. Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle;Niewoehner;Neuron,2014

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