Bile salt export pump inhibitors are associated with bile acid-dependent drug-induced toxicity in sandwich-cultured hepatocytes
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference33 articles.
1. Drug-induced liver disorders: implications for drug development and regulation;Kaplowitz;Drug Saf.,2001
2. Why drugs fail – A study on side effects in new chemical entities;Schuster;Curr. Pharm. Des,2005
3. Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver;Stieger;Gastroenterology,2000
4. The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions;Fattinger;Clin. Pharmacol. Ther.,2001
5. The human bile salt export pump: characterization of substrate specificity and identification of inhibitors;Byrne;Gastroenterology,2002
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