Glycosylation of onconase increases its conformational stability and toxicity for cancer cells

Author:

Kim Byung-Moon,Kim Hana,Raines Ronald T,Lee Younghoon

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference41 articles.

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3. Cancer chemotherapy—ribonucleases to the rescue;Leland;Chem. Biol.,2001

4. Onconase: an unusually stable protein;Notomista;Biochemistry,2000

5. I human clinical trial of ONCONASE (P-30 protein) administered intravenously on a weekly schedule in cancer patients with solid tumors;Mikulski;Int. J. Oncol.,1993

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