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Treating brain diseases using systemic parenterally-administered protein therapeutics: Dysfunction of the brain barriers and potential strategies

  • Published:2021-02 Issue: Volume:269 Page:120461
  • ISSN:0142-9612
  • Container-title:Biomaterials
  • language:en
  • Short-container-title:Biomaterials

Author:

Zaghmi A.,Drouin-Ouellet J.,Brambilla D.,Gauthier M.A.

Funder

Fonds de Recherche du Québec - Santé

Natural Sciences and Engineering Research Council of Canada

Publisher

Elsevier BV

Subject

Mechanics of Materials,Biomaterials,Biophysics,Ceramics and Composites,Bioengineering

Reference553 articles.

1. In vivo properties of therapeutic bioconjugates composed of proteins and architecturally/functionally complex polymers;Zaghmi,2019

2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings;Lipinski;Adv. Drug Deliv. Rev.,2001

3. Structure and function of the intercellular junctions: barrier of paracellular drug delivery;Zheng;Curr. Pharmaceut. Des.,2006

4. Measuring size-dependent permeability of the tight junction using PEG profiling;Van Itallie;Methods Mol. Biol.,2011

5. Agile delivery of protein therapeutics to CNS;Yi;J. Contr. Release,2014

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2. Peptide and protein in therapeutics;Peptide and Protein Drug Delivery Using Polysaccharides;2024

3. Molecular Trojan Horses for treating lysosomal storage diseases;Molecular Genetics and Metabolism;2023-11

4. Engineering blood-brain barrier-permeable and tumor cell-ingestible pro-proteins for glioblastoma treatment;Science China Chemistry;2023-08-14

5. Biologics for the management of dementia;Nanomedicine-Based Approaches for the Treatment of Dementia;2023
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