Novel selenylated imidazo[1,2-a]pyridines for breast cancer chemotherapy: Inhibition of cell proliferation by Akt-mediated regulation, DNA cleavage and apoptosis

Author:

Almeida Gabriela M.,Rafique JamalORCID,Saba Sumbal,Siminski Tâmila,Mota Nádia S.R.S.,Filho Danilo Wilhelm,Braga Antonio Luiz,Pedrosa Rozangela Curi,Ourique Fabiana

Funder

CAPES

CNPq

CEBIME

CERSusChem GSK/FAPESP

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference34 articles.

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2. A novel imidazopyridine PI3K inhibitor with anticancer activity in non-small cell lung cancer cells;Lee;Oncol. Rep.,2013

3. Synthesis and anti-in fl ammatory evaluation of novel benzimidazole and imidazopyridine derivatives;Chen;ACS Med. Chem. Lett.,2013

4. Bimodal actions of selenium essential for antioxidant and toxic pro-oxidant activities: the selenium paradox (Review);Lee;Mol. Med. Rep.,2012

5. Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stages;Zou;ACS Med. Chem. Lett.,2014

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