Trimethylamine N-oxide induces inflammation and endothelial dysfunction in human umbilical vein endothelial cells via activating ROS-TXNIP-NLRP3 inflammasome-Reference-Cited by-同舟云学术

Trimethylamine N-oxide induces inflammation and endothelial dysfunction in human umbilical vein endothelial cells via activating ROS-TXNIP-NLRP3 inflammasome

Published:2016-12 Issue:1-2 Volume:481 Page:63-70
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Sun Xiaolei,Jiao Xuefei,Ma Yarong,Liu Yong,Zhang Lei,He Yanzheng,Chen Yunhui^ORCID

Funder

Sichuan Medical Association Fund of China

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference31 articles.

1. Trimethylamine-N-oxide: a link between the gut microbiome, bile acid metabolism, andatherosclerosis;Wilson;Curr. Opin. Lipidol.,2016

2. New insight into the dietary cause of atherosclerosis: implications for pharmacology;Spector;J. Pharmacol. Exp. Ther.,2016

3. Dysbiosis of gut microbiota with reduced trimethylamine-N-oxide level in patients with large-artery atherosclerotic stroke or transient ischemic attack;Yin;J. Am. Heart Assoc.,2015

4. Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet;Gao;J. Biosci. Bioeng.,2014

5. A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat;Xu;BMC Genomics,2015

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