Crystallographic study of multi-drug resistant HIV-1 protease lopinavir complex: Mechanism of drug recognition and resistance-Reference-Cited by-同舟云学术

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Crystallographic study of multi-drug resistant HIV-1 protease lopinavir complex: Mechanism of drug recognition and resistance

Published:2013-07 Issue:2 Volume:437 Page:199-204
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Liu Zhigang,Yedidi Ravikiran S.,Wang Yong,Dewdney Tamaria G.,Reiter Samuel J.,Brunzelle Joseph S.,Kovari Iulia A.,Kovari Ladislau C.

Funder

the National Institutes of Health Grant

the American Foundation for AIDS Research

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference23 articles.

1. No cure yet for HIV-1, but therapeutic research presses on;Schooley;J. Infect. Dis.,2007

2. Highly active antiretroviral therapy in HIV-associated pulmonary hypertension;Barbaro;Minerva Cardioangiol.,2005

3. Low fidelity of cell-free DNA synthesis by reverse transcriptase of human immunodeficiency virus;Takeuchi;J. Virol.,1988

4. In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease;Partaledis;J. Virol.,1995

5. Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease;Patick;Antimicrob. Agents Chemother.,1996

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1. The crystal structure of the host-guest complex: N ^′-{5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl}-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide-diethyl ether (2/1);Zeitschrift für Kristallographie - New Crystal Structures;2024-01-19

2. Evolution of drug resistance drives destabilization of flap region dynamics in HIV-1 protease;Biophysical Reports;2023-09

3. Evolution of drug resistance drives progressive destabilizations in functionally conserved molecular dynamics of the flap region of the HIV-1 protease;2022-11-24

4. An insight to the molecular interactions of the FDA approved HIV PR drugs against L38L↑N↑L PR mutant;Journal of Computer-Aided Molecular Design;2018-02-03

5. Investigation of the binding free energies of FDA approved drugs against subtype B and C-SA HIV PR: ONIOM approach;Journal of Molecular Graphics and Modelling;2017-09

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