An insight to the molecular interactions of the FDA approved HIV PR drugs against L38L↑N↑L PR mutant-Reference-Cited by-同舟云学术

An insight to the molecular interactions of the FDA approved HIV PR drugs against L38L↑N↑L PR mutant

Published:2018-02-03 Issue:3 Volume:32 Page:459-471
ISSN:0920-654X
Container-title:Journal of Computer-Aided Molecular Design
language:en
Short-container-title:J Comput Aided Mol Des

Author:

Sanusi Zainab K.,Govender Thavendran,Maguire Glenn E. M.,Maseko Sibusiso B.,Lin Johnson,Kruger Hendrik G.,Honarparvar Bahareh^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry,Computer Science Applications,Drug Discovery

Link

http://link.springer.com/article/10.1007/s10822-018-0099-9/fulltext.html

Reference114 articles.

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3. Brik A, Wong C-H (2003) HIV-1 protease: mechanism and drug discovery. Org Biomol Chem 1(1):5–14

4. Pearl LH, Taylor WR (1987) A structural model for the retroviral proteases. Nature 329(6137):351–354

5. Mildner AM et al (1994) The HIV-1 protease as enzyme and substrate: mutagenesis of autolysis sites and generation of a stable mutant with retained kinetic properties. Biochemistry 33(32):9405–9413

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