In vivo toxicology of excipients commonly employed in drug discovery in rats

Author:

Gopinathan Suma,O’Neill Emily,Rodriguez Lawrence A.,Champ Rose,Phillips Megan,Nouraldeen Amr,Wendt Mary,Wilson Alan G.E.,Kramer Jeffrey A.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference24 articles.

1. Chronic toxicity studies on methylcellulose in rats;Bauer;Journal of the American Pharmaceutical Association. American Pharmaceutical Association,1951

2. Impact of Solutol HS 15 on the pharmacokinetic behaviour of colchicine upon intravenous administration to male Wistar rats;Bittner;Biopharmaceutics & Drug Disposition,2003

3. Impact of oral administration of the surface-active excipient solutol HS 15 on the pharmacokinetics of intravenously administered colchicine;Bittner;Letters in Drug Design & Discovery,2005

4. The acute oral toxicity of corn oil;Boyd;The Journal of Clinical Pharmacology and the Journal of New Drugs,1969

5. Improved oral bioavailability of cyclosporin A in male Wistar rats. Comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension;Bravo Gonzalez;International Journal of Pharmaceutics,2002

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