Comparison of rat and dog models of vasodilatation and lipolysis for the calculation of a therapeutic index for GPR109A agonists

Author:

Carballo-Jane Ester,Gerckens Lynn S.,Luell Silvi,Parlapiano Allison S.,Wolff Michael,Colletti Steven L.,Tata James R.,Taggart Andrew K.P.,Waters M. Gerard,Richman Jeremy G.,McCann Margaret E.,Forrest Michael J.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference31 articles.

1. Studies on the mechanism of flush induced by nicotinic acid;Andersson;Acta Pharmacologica et Toxicologica (Copenhagen),1977

2. GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing;Benyo;Journal of Clinical Investigation,2005

3. Potential role for epidermal Langerhans cells in nicotinic acid-induced vasodilatation in the mouse;Carballo-Jane;Inflammation Research,2007

4. Nicotinic acid: The broad-spectrum lipid drug. A 50th anniversary review;Carlson;Journal of Internal Medicine,2005

5. Nicotinic acid and other therapies for raising high-density lipoprotein;Carlson;Current Opinion in Cardiology,2006

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