Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation

Author:

Guo Liang,Guthrie Heather

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference24 articles.

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2. PatchXpress 7000A automated patch-clamp system vs. convention patch clamp technique as applied for pharmacological screens on HERG potassium channels. Inaugural users group meeting;Cerne,2004

3. The long QT syndromes: Genetic basis and clinical implications;Chiang;Journal of the American College of Cardiology,2000

4. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome;Curran;Cell,1995

5. Dubin, A. E., Nasser, N., Rohrbacher, J., Hermans, A. N., Marrannes, R., Grantham, C., et al. (in press). Identifying modulators of hERG channel activity using the PatchXpress TM planar patch clamp. Journal of Biomolecular Screening.

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