Investigating dynamic protocol-dependence of hERG potassium channel inhibition at 37°C: Cisapride versus dofetilide
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference56 articles.
1. Mechanism of hERG K+channel blockade by the fluoroquinolone antibiotic moxifloxacin;Alexandrou;British Journal of Pharmacology,2006
2. Voltage- and time-dependent block of the delayed rectifier K+ current in cardiac myocytes by dofetilide;Carmeliet;Journal of Pharmacology and Experimental Therapeutics,1992
3. Drugs that prolong QT interval as an unwanted effect: Assessing their likelihood of inducing hazardous cardiac dysrhythmias;Cavero;Expert Opinion on Pharmacotherapy,2000
4. Validation of a [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels;Chiu;Journal of Pharmacological Sciences,2004
5. Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin;Duncan;Biochemical Pharmacology,2007
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