Comparing the sensitivity of cross-over and parallel study designs for QTc assessment: An analysis based on a single large study of moxifloxacin in 48 nonhuman primates-Reference-Cited by-同舟云学术

Comparing the sensitivity of cross-over and parallel study designs for QTc assessment: An analysis based on a single large study of moxifloxacin in 48 nonhuman primates

Published:2023-09 Issue: Volume:123 Page:107299
ISSN:1056-8719
Container-title:Journal of Pharmacological and Toxicological Methods
language:en
Short-container-title:Journal of Pharmacological and Toxicological Methods

Author:

Leishman Derek J.,Holdsworth David L.,Best Derek D.,Roche Brian M.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference18 articles.

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4. ICH E14/S7B implementation working group - clinical and nonclinical evaluation of QT/QTc interval prolongation and proarrhythmic potential. Questions and answers;Anonymous.,2022

5. Review of the statistical analysis of the dog telemetry study;Aylott;Pharmaceutical Statistics,2011

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