Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment-Reference-Cited by-同舟云学术

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Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment

Published:2013-07 Issue:1 Volume:68 Page:112-122
ISSN:1056-8719
Container-title:Journal of Pharmacological and Toxicological Methods
language:en
Short-container-title:Journal of Pharmacological and Toxicological Methods

Author:

Elkins Ryan C.,Davies Mark R.,Brough Stephen J.,Gavaghan David J.,Cui Yi,Abi-Gerges Najah,Mirams Gary R.

Funder

GlaxoSmithKline Grants & Affiliates

EPSRC Cross-Discipline Interface Programme

Microsoft Research, and an NC3Rs/EPSRC Strategic Award in Mathematics and Toxicology

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference37 articles.

1. Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge;Beattie;Journal of Pharmacological and Toxicological Methods,2013

2. Optimisation and validation of a medium-throughput electrophysiology-based hERG assay using IonWorks ht;Bridgland-Taylor;Journal of Pharmacological and Toxicological Methods,2006

3. Models of cardiac tissue electrophysiology: Progress, challenges and open questions;Clayton;Progress in Biophysics and Molecular Biology,2011

4. Considerations for the use of cellular electrophysiology models within cardiac tissue simulations;Cooper;Progress in Biophysics and Molecular Biology,2011

5. High-throughput functional curation of cellular electrophysiology models;Cooper;Progress in Biophysics and Molecular Biology,2011

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