Application of directed evolution and back-to-consensus algorithms to human alpha1-antitrypsin leads to diminished anti-protease activity and augmented anti-inflammatory activities-Reference-Cited by-同舟云学术

Application of directed evolution and back-to-consensus algorithms to human alpha1-antitrypsin leads to diminished anti-protease activity and augmented anti-inflammatory activities

Published:2020-09 Issue: Volume:355 Page:104135
ISSN:0008-8749
Container-title:Cellular Immunology
language:en
Short-container-title:Cellular Immunology

Author:

Lior Yotam,Jasevitch Maria,Ochayon David E.,Zaretsky Mariana,Lewis Eli C.,Aharoni Amir

Publisher

Elsevier BV

Subject

Immunology

Reference67 articles.

1. Alpha 1-antitrypsin: structure, function and molecular biology of the gene;Kalsheker;Biosci. Rep.,1989

2. Point mutation of a non-elastase-binding site in human alpha1-antitrypsin alters its anti-inflammatory properties;Lior;Front. Immunol.,2018

3. Acute-phase protein alpha1-anti-trypsin: diverting injurious innate and adaptive immune responses from non-authentic threats;Guttman;Clin. Exp. Immunol.,2015

4. Expanding the clinical indications for alpha(1)-antitrypsin therapy;Lewis;Mol. Med.,2012

5. Therapy with plasma purified alpha1-antitrypsin (Prolastin(R)) induces time-dependent changes in plasma levels of MMP-9 and MPO;Koepke;PLoS ONE,2015

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development of anti-inflammatory peptidomimetics based on the structure of human alpha1-antitrypsin;European Journal of Medicinal Chemistry;2022-01

2. Boosted Pro-Inflammatory Activity in Human PBMCs by Lipopolysaccharide and SARS-CoV-2 Spike Protein Is Regulated by α-1 Antitrypsin;International Journal of Molecular Sciences;2021-07-26