IL-17RA aptamer-mediated repression of IL-6 inhibits synovium inflammation in a murine model of osteoarthritis

Author:

Chen L.,Li D.Q.,Zhong J.,Wu X.L.,Chen Q.,Peng H.,Liu S.Q.

Publisher

Elsevier BV

Subject

Orthopedics and Sports Medicine,Biomedical Engineering,Rheumatology

Reference34 articles.

1. Contribution of interleukin 17 to human cartilage degradation and synovial inflammation in osteoarthritis;Honorati;Osteoarthritis Cartilage,2002

2. Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1beta;Benderdour;J Rheumatol,2002

3. Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts;Honorati;Osteoarthritis Cartilage,2006

4. Synergism between tumor necrosis factor alpha and interleukin-17 to induce IL-23 p19 expression in fibroblast-like synoviocytes;Goldberg;Mol Immunol,2009

5. In-vitro-induced Th17 cells fail to induce inflammation in vivo and show an impaired migration into inflamed sites;Janke;Eur J Immunol,2010

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