Synergism between tumor necrosis factor alpha and interleukin-17 to induce IL-23 p19 expression in fibroblast-like synoviocytes

Author:

Goldberg Michael,Nadiv Orna,Luknar-Gabor Noemi,Agar Gabriel,Beer Yiftah,Katz Yitzhak

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference29 articles.

1. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17;Aggarwal;J. Biol. Chem.,2003

2. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha;Albanesi;J. Immunol.,1999

3. IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts;Andoh;J. Immunol.,2002

4. Abundant expression of the IL-23 subunit p19, but low levels of bioactive IL-23 in the rheumatoid synovium;Brentano;Ann. Rheum. Dis.,2009

5. IL-23 and IL-17 in pathogenesis of experimental ocular autoimmunity: requirement for IL–23 may extend beyond its role in sustaining the IL-17 effector response;Caspi;J. Immunol.,2007

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