Gq-Gi-PLCβ in cells: More than the sum of its reconstituted parts
Author:
Funder
National Cancer Institute
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Physiology
Reference10 articles.
1. Heterotrimeric G protein subunit Gαq is a master switch for Gβγ-mediated calcium mobilization by Gi-coupled GPCRs;Pfeil;Mol. Cell,2020
2. Activation of phospholipase Cβ by Gβγ and Gαq involves C-terminal rearrangement to release autoinhibition;Fisher;Structure,2020
3. An autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Gαq activation;Lyon;Nat. Struct. Mol. Biol.,2011
4. The experimental power of FR900359 to study Gq-regulated biological processes;Schrage;Nat. Commun.,2015
5. Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins;Mukhopadhyay;Proc. Natl. Acad. Sci. U. S. A.,1999
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