Higher baseline expression of the PTGS2 gene and greater decreases in total colonic fatty acid content predict greater decreases in colonic prostaglandin-E2 concentrations after dietary supplementation with ω-3 fatty acids

Author:

Wilson Matthew J.,Sen Ananda,Bridges DaveORCID,Turgeon D. KimORCID,Brenner Dean E.,Smith William L.,Ruffin Mack T.ORCID,Djuric Zora

Funder

NIH

Gastro-Intestinal SPORE

University of Michigan Rogel Comprehensive Cancer Center

Clinical Translational Science Award, NIH

Michigan Diabetes Research Center, NIH

Michigan Nutrition and Obesity Research Center, NIH

Kutsche Family Memorial Endowment

Rose and Lawrence C. Page Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry

Reference39 articles.

1. Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal neoplasia;Hull;Recent Results Cancer Res.,2013

2. The anti-inflammatory effect of personalized omega-3 fatty acid dosing for reducing prostaglandin E2 in the colonic mucosa is attenuated in obesity;Djuric;Cancer Prev. Res. (Phila).,2017

3. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally, occuring plant phenolic compound;Rao;Cancer Res.,1995

4. Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent;Rao;Cancer Res.,1995

5. Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats;Reddy;Carcinogenesis,1993

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