Chemical protein synthesis elucidates key modulation mechanism of the tyrosine-O-sulfation in inducing strengthened inhibitory activity of hirudin
Author:
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangdong Province
Publisher
Elsevier BV
Subject
General Chemistry
Reference30 articles.
1. Hirudin As Alternative Anticoagulant- A Historical Review
2. Kinetics of the inhibition of thrombin by hirudin
3. Leech-Derived Thrombin Inhibitors: From Structures to Mechanisms to Clinical Applications
4. Refined structure of the Hirudin-thrombin complex
5. The Structure of a Complex of Recombinant Hirudin and Human α-Thrombin
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