A novel small molecule inhibitor of the DNA repair protein Ku70/80-Reference-Cited by-同舟云学术

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A novel small molecule inhibitor of the DNA repair protein Ku70/80

Published:2016-07 Issue: Volume:43 Page:98-106
ISSN:1568-7864
Container-title:DNA Repair
language:en
Short-container-title:DNA Repair

Author:

Weterings Eric,Gallegos Alfred C.,Dominick Lauren N.,Cooke Laurence S.,Bartels Trace N.,Vagner Josef,Matsunaga Terry O.,Mahadevan Daruka

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference27 articles.

1. The Ku70/80 ring in Non-homologous End-joining: easy to slip on hard to remove;Kragelund;Front Biosci. (Landmark Ed),2016

2. DNA repair dysregulation from cancer driver to therapeutic target;Curtin;Nat. Rev. Cancer,2012

3. Strategies for optimizing the response of cancer and normal tissues to radiation;Moding;Nat. Rev. Drug Discovery,2013

4. Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining;Ghezraoui;Mol. Cell,2014

5. Targeted radiosensitization of ETS fusion-positive prostate cancer through PARP1 inhibition;Han;Neoplasia,2013

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1. How to Shift the Equilibrium of DNA Break Repair in Favor of Homologous Recombination;Molecular Biology;2024-08

2. Discovery of UMI-77 as a novel Ku70/80 inhibitor sensitizing cancer cells to DNA damaging agents in vitro and in vivo;European Journal of Pharmacology;2024-07

3. Improving homology‐directed repair by small molecule agents for genetic engineering in unconventional yeast?—Learning from the engineering of mammalian systems;Microbial Biotechnology;2024-02

4. Double‐strand DNA break repair: molecular mechanisms and therapeutic targets;MedComm;2023-10

5. Advancements in pre-clinical development of gene editing-based therapies to treat inherited retinal diseases;Vision Research;2023-08

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