Small Cell Cancer Transformation of Lung Adenocarcinoma During Durvalumab Treatment After Chemoradiotherapy
Author:
Funder
Ono Pharmaceutical
Bristol-Myers Squibb
AstraZeneca
NEC
Roche
Chugai
Lilly
MSD
Novartis
Kyowa Hakko Kirin
Amgen
Ignyta
Publisher
Elsevier BV
Subject
Pulmonary and Respiratory Medicine,Oncology
Reference5 articles.
1. Clonal history and genetic predictors of transformation into small-cell carcinomas from lung adenocarcinomas;Lee;J Clin Oncol,2017
2. Small cell lung cancer transformation as a mechanism of resistance to PD-1 therapy in KRAS-mutant lung adenocarcinoma: a report of two cases;Iams;J Thorac Oncol,2018
3. Overall survival with durvalumab after chemoradiotherapy in stage III NSCLC;Antonia;N Engl J Med,2018
4. RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer;Niederst;Nat Commun,2015
5. Concurrent RB1 and TP53 alterations define a subset of EGFR-mutant lung cancers at risk for histologic transformation and inferior clinical outcomes;Offin;J Thorac Oncol,2019
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2. Case Report: Re-Sensitization to Gefitinib in Lung Adenocarcinoma Harboring EGFR Mutation and High PD-L1 Expression After Immunotherapy Resistance, Which Finally Transform Into Small Cell Carcinoma;Frontiers in Oncology;2021-06-24
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