Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response-Reference-Cited by-同舟云学术

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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

Published:2019-04 Issue:4 Volume:24 Page:551-565.e8
ISSN:1934-5909
Container-title:Cell Stem Cell
language:en
Short-container-title:Cell Stem Cell

Author:

Schiroli Giulia,Conti Anastasia,Ferrari Samuele,della Volpe Lucrezia,Jacob Aurelien,Albano Luisa,Beretta Stefano,Calabria Andrea,Vavassori Valentina,Gasparini Patrizia,Salataj Eralda,Ndiaye-Lobry Delphine,Brombin Chiara,Chaumeil Julie,Montini Eugenio,Merelli Ivan,Genovese Pietro,Naldini Luigi,Di Micco Raffaella

Funder

Telethon

Italian Ministry of Health

San Raffaele Hospital

Human Frontier Science Program

ATIP-Avenir

INSERM/CNRS

French Cancer Research Association

Fondazione Caligara

FIRC-AIRC

Publisher

Elsevier BV

Subject

Cell Biology,Genetics,Molecular Medicine

Reference58 articles.

1. Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle;Beerman;Cell Stem Cell,2014

2. Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation;Biechonski;Sci. Rep.,2018

3. Characterization of the interplay between DNA repair and CRISPR/Cas9-induced DNA lesions at an endogenous locus;Bothmer;Nat. Commun.,2017

4. Easy quantification of template-directed CRISPR/Cas9 editing;Brinkman;Nucleic Acids Res.,2018

5. Integrating single-cell transcriptomic data across different conditions, technologies, and species;Butler;Nat. Biotechnol.,2018

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1. Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47 -deficient chronic granulomatous disease;Molecular Therapy - Nucleic Acids;2024-09

2. DNA-PK inhibition enhances gene editing efficiency in HSPCs for CRISPR-based treatment of X-linked hyper IgM syndrome;Molecular Therapy - Methods & Clinical Development;2024-09

3. Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editing;2024-08-29

4. In vivo liver targeted genome editing as therapeutic approach: progresses and challenges;Frontiers in Genome Editing;2024-08-23

5. Reprogramming human B cells with custom heavy-chain antibodies;Nature Biomedical Engineering;2024-07-22

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