Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors-Reference-Cited by-同舟云学术

Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors

Published:1996-08 Issue:8 Volume:4 Page:1247-1253
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Faerman Carlos H.,Savvides Savvas N.,Strickland Corey,Breidenbach Mark A.,Ponasik James A.,Ganem Bruce,Ripoll Daniel,Luise Krauth-Siegel R.,Andrew Karplus P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference40 articles.

1. Rationally designed selective inhibitors of trypanothione reductase. Phenothiazines and related tricyclics as lead structures

2. Molecular studies on trypanothione reductase, a target for antiparasitic drugs

3. Disulfide-Reductase Inhibitors as Chemotherapeutic Agents: The Design of Drugs for Trypanosomiasis and Malaria

4. Active site of trypanothione reductase

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